Table 2.
Bivariate analysis of outcome measures of scrub typhus (n = 120).
| Characteristics | Mortality | p value | |
|---|---|---|---|
| No | Yes | ||
| n (%) | n (%) | ||
| aAge in years | 40.0 (30.8) | 46.5 (31.8) | 0.114 |
| Sex (female) | 62 (79.5) | 16 (20.5) | 1.000 |
| Duration of fever | |||
| <7 days | 48 (75.0) | 16 (25.0) | 0.149 |
| 7–14 days | 43 (84.3) | 8 (15.7) | |
| 15–21 days | 5 (100.0) | 0 | |
| HR (>100/minute) | 61 (72.6) | 23 (27.4) | <0.001∗∗ |
| SBP (<90 mmHg) | 41 (70.7) | 17 (29.3) | 0.025∗ |
| DBP (<60 mmHg) | 42 (71.2) | 17 (28.8) | 0.032∗ |
| Hemoglobin level (<12 mg/dl) | 83 (79.0) | 22 (21.0) | 0.733 |
| WBC count (>11000 per mm3) | 57 (76.0) | 18 (24.0) | 0.239 |
| Platelets count (<100000 per mm3) | 70 (76.9) | 21 (23.1) | 0.220 |
| Bilirubin level (>1.5 mg/dl) | 34 (70.8) | 14 (29.2) | 0.069 |
| Total protein level (<6 g/dl) | 59 (75.6) | 19 (24.4) | 0.165 |
| Albumin level (<3.5 g/dl) | 72 (77.4) | 21 (22.6) | 0.299 |
| Transaminase level (>120 IU/l) | 52 (80.0) | 13 (20.0) | 1.000 |
| Serum creatinine level (>1.4 mg/dl) | 26 (57.8) | 19 (42.2) | <0.001∗∗ |
| AKI requiring dialysis | 3 (42.9) | 4 (57.1) | 0.029∗ |
| ARDS | 31 (56.4) | 24 (43.6) | <0.001∗∗ |
| Shock requiring vasopressor | 46 (65.7) | 24 (34.3) | <0.001∗∗ |
| Meningoencephalitis | 8 (61.5) | 5 (38.5) | 0.113 |
| GI bleeding | 1 (50.0) | 1 (50.0) | 0.361 |
| Pneumonia | 24 (88.9) | 3 (11.1) | 0.299 |
| Arrhythmia | 1 (100.0) | 0 (0) | 1.000 |
| Myocarditis | 4 (50.0) | 4 (50.0) | 0.500 |
aMedian [interquartile range (IQR)], ARDS: acute respiratory distress syndrome; AKI: acute kidney injury; DBS: diastolic blood pressure; HR: heart rate; SBP: systolic blood pressure; WBC: white blood cell. ∗Significant at p < 0.05 and ∗∗significant at p < 0.001.