Table 1.

Hematology and clinical chemistry in sheep with mild or severe left ventricular myocardial infarcts

			Baseline		24 h after infarction		3 wk after infarction		12 wk after infarction
	Reference range	Mild	Severe	Mild	Severe	Mild	Severe	Mild	Severe
Hematology
Hgb	8.5–14.8 g/dL	12.7 ± 0.4	12.3 ± 0.7	8.9 ± 1.3	9.2 ± 0.7	10.2 ± 0.9	9.6 ± 0.3	10.3 ± 0.4	10.6 ± 0.6
WBC	3.8–11.5 ×103 cells/μL	6.3 ± 0.5	5.7 ± 0.7	8.5 ± 0.3	7.4 ± 0.8	6.0 ± 0.5	4.9 ± 0.9	5.2 ± 0.5	5.6 ± 0.6
RBC	8.5–15.5 ×103 cells/μL	11.2 ± 0.7	10.7 ± 1.3	8.6 ± 0.3	8.2 ± 0.9	9.3 ± 1.9	10.3 ± 1.4	9.9 ± 0.4	9.5 ± 1.0
Hct	27%–45%	36.7 ± 1.6	33.9 ± 1.5	26.8 ± 1.5	28.7 ± 1.1	29.6 ± 1.6	31.2 ± 1.8	32.3 ± 1.9	30.8 ± 1.2
Platelets	150–750 ×103 cells/μL	436.3 ± 66.0	426.8 ± 57.0	322.7 ± 77.0	356.8 ± 47.0	362.0 ± 52.0	432.0 ± 56.0	388.7 ± 40.0	322.7 ± 87.0
Neutrophils	10.5%–55.0%	30.1 ± 3.2	35.5 ± 2.9	40.7 ± 3.8	43.3 ± 4.2	28.9 ± 2.3	26.9 ± 3.4	29.8 ± 1.9	31.8 ± 3.1
Lymphocytes	42%–75%	61.8 ± 4.8	65.8 ± 3.2	73.8 ± 3.8	74.3 ± 2.7	63.7 ± 4.7	60.6 ± 5.9	56.3 ± 3.6	52.6 ± 2.9
Kidney function
BUN	8.5–35 mg/dL	14.6 ± 2.2	13.6 ± 1.9	16.5 ± 3.2	15.9 ± 3.2	14.2 ± 2.9	17.9 ± 4.8	17.3 ± 3.2	16.8 ± 4.0
Creatinine	0.4–1.9 mg/dL	0.75 ± 0.09	1.3 ± 0.2	1.6 ± 0.1	1.4 ± 0.1	1.2 ± 0.1	0.9 ± 0.1	1.2 ± 0.1	1.1 ± 0.1
Liver function
ALT	20–38 U/L	26.1 ± 4.4	28.3 ± 3.2	33.2 ± 3.3	35.1 ± 2.8	27.9 ± 3.0	33.9 ± 3.9	25.1 ± 2.9	28.4 ± 4.0
ALP	70–390 U/L	165 ± 27	155 ± 37	288 ± 26	302 ± 30	187 ± 26	245 ± 47	193 ± 42	266 ± 36
Total bilirubin	0.1–0.5 mg/dL	0.14 ± 0.03	0.16 ± 0.04	0.43 ± 0.03	0.35 ± 0.05	0.34 ± 0.08	0.20 ± 0.09	0.22 ± 0.02	0.38 ± 0.03
Cardiac enzymes
Troponin I	< 0.03 ng/mL	0.01± 0.00	0.01 ± 0.00	26.7 ± 2.8b	26.7 ± 2.8c	0.13 ± 0.00	0.09 ± 0.008	0.02 ± 0.00	0.02 ± 0.01
Total creatine phosphokinase I	49–397 U/L	64 ± 2.1	80 ± 3.8	2154 ± 344c	6884 ± 286c	369 ± 48a	324 ± 38a	123 ± 23	188 ± 48

^aP < 0.05 compared with baseline value for this group.

^bP < 0.01 compared with baseline value for this group.

^cP < 0.001 compared with baseline value for this group.