Table 2.
Individual clinical characteristics of SSc patients with pericardial disease.
| Patient | Age | Type of SSc | Diagnosis | Overlap syndrome | Size of pericardial effusion | Presence of tamponade | Right heart failure | Procedure | Fluid study | Meds prior to admission |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 60 | Unknown | M-L | - | Severe | |||||
| 2 | 71 | Limited | + (PM, MCTD) | M | - | Mild | Thoracentesis | Pleural fluid: transudative (LDH 88, Pr 1.3, NUC 63, seg 52) | ||
| 3 | 60 | Unknown | L | - | Severe | Iloprost, sildenafil, bosentan, and plaquenil | ||||
| 4 | 68 | Unknown | M-L | - | ||||||
| 5 | 62 | Limited | New | M-L | + | Severe | ||||
| 6 | 61 | Diffuse | M-L | - | Methylprednisolone | |||||
| 7 | 55 | Limited | M | - | Mild | Treprostinil, macitentan, sildenafil | ||||
| 8 | 65 | Unknown | S | - | Mycophenolate, tacrolimus, and prednisone | |||||
| 9 | 79 | Unknown | L | - | Severe | |||||
| 10 | 66 | Limited | 28 yrs | M | - | Ambrisentan, nifedipine | ||||
| 11 | 57 | Unknown | M | - | Nifedipine | |||||
| 12 | 49 | Unknown | M | - | ||||||
| 13 | 72 | Unknown | New | M | - | Moderate | Nifedipine, ibuprofen | |||
| 14 | 59 | Unknown | New | + (IBM) | M-L | - | ||||
| 15 | 63 | Limited | 2 yrs | + (Sicca) | M | - | Severe | Cevimeline, candesartan | ||
| 16 | 58 | Unknown | 13 yrs | L | - | Moderate | Ambrisentan, sildenafil, iloprost, and mycophenolate | |||
| 17 | 57 | Unknown | 14 yrs | M-L | + | Severe | Thoracentesis | Macitentan, mycophenolate, and sildenafil | ||
| 18 | 56 | Limited | L | + | Mod-severe | Sildenafil | ||||
| 19 | 56 | Diffuse | 2 mo | L | - | Pericardiocentesis | WBC 178, RBC 9, GS neg, Cx neg, cytology neg | Methotrexate, prednisone | ||
| 20 | 48 | Diffuse | 8 yrs | + (MCTD) | L | - | Pericardiocentesis → pericardial window | WBC 240, RBC 3550, pleural fluid: no malignancy, reactive mesothelial cells, and chronic inflammation | Lisinopril | |
| 21 | 44 | Diffuse | New | L | - | Pericardiocentesis → pericardial window | Cytology neg, AFB neg | |||
| 22 | 66 | Diffuse | New | L | + | Pericardiocentesis → pericardial window | WBC 568, RBC 815, GS neg, and cytology neg | Prednisone | ||
| 23 | 45 | Diffuse | 7 mo | + (RA, Sjogren, DM) | M | - | Pericardial window | Methotrexate, plaquenil |
S = small, M = moderate, L = large, PM = polymyositis, IBM = inclusion body myositis, MCTD = mixed connective tissue disease, RA = rheumatoid arthritis, and DM = dermatomyositis.