Supplementary Figure 1.

Disease activity index subscores for WT, ERβ-KO, and ERα-KO mice on DSS. 2.5% DSS-fed mice were assessed on day 5 for extent of (A) weight loss, (B) stool consistency, and (C) rectal bleeding. Data are represented as the means ± SEM 7–17 individual mice/group. *P ≤ .05, **P ≤ .01, and ***P ≤ .001.