Reproductive hormone release following GnRH and vehicle in young and older men. Mean ± standard deviation of serum hormonal response to GnRH 0.1 nmol/kg/h and vehicle in young (n = 10) (a, b) and older men (n = 5/group) (c, d). Serum LH (IU/L) is shown in blue, serum FSH (IU/L) in red, and serum testosterone (nmol/L) in purple. FSH, follicle-stimulating hormone; GnRH, gonadotropin-releasing hormone; LH, luteinising hormone; Testo, testosterone.