Table 1.
Therapeutic areas and technologies by study design
| Interventional trials (n = 22) |
Observational studies (n = 66) |
|||
|---|---|---|---|---|
| n (%) | Ref. | n (%) | Ref. | |
| Therapeutic area | ||||
| Cardiology | 3 (14) | 17, 19, 25 | 16 (24) | 31, 37–40, 53–63 |
| Diabetes | 5 (28) | 11, 12, 24, 26, 28 | 8 (12) | 30, 31, 41, 64–68 |
| Sleep | 3 (14) | 15, 20, 21 | 7 (11) | 32, 34–36, 69–71 |
| Obesity | 0 (0) | - | 9 (14) | 30, 72–79 |
| Geriatrics | 0 (0) | - | 9 (14) | 80–88 |
| Neurology | 1 (5) | 13 | 3 (5) | 44, 46, 89 |
| Reproductive and peripartum health | 2 (9) | 8, 10 | 2 (3) | 90, 91 |
| Orthopedics | 1 (5) | 22 | 3 (5) | 92–94 |
| Pulmonology | 0 (0) | - | 3 (5) | 95–97 |
| Arthritis | 1 (5) | 16 | 2 (3) | 93, 98 |
| Psychology | 0 (0) | - | 3 (5) | 78, 99, 100 |
| Cancer | 3 (14) | 14, 18, 23 | 0 (0) | - |
| Nephrology | 0 (0) | - | 2 (3) | 33, 101 |
| Gastroenterology | 1 (5) | 29 | 1 (2) | 43 |
| Nutrition | 1 (5) | 27 | 1 (2) | 32 |
| Device | ||||
| Wearable inertial sensor/accelerometer | 16 (73) | 8, 9, 12, 14–25, 27 | 59 (89) | 30, 32–36, 44, 46, 53–103 |
| Biosensor | 6 (28) | 11, 12, 24, 26, 28, 29 | 7 (11) | 31, 33, 37, 39–41, 43 |
| Continuous glucose monitor | 5 (23) | 11, 12, 24, 26, 28 | 1 (2) | 41 |
| Electrocardiograph | 0 (0) | - | 2 (3) | 31, 40 |
| Ingestible pH monitor | 1 (5) | 29 | 1 (2) | 43 |
| Ambulatory blood pressure monitor | 0 (0) | - | 1 (2) | 39 |
| Implantable cardioverter-defibrillator | 0 (0) | - | 1 (2) | 37 |
| Heart rate monitor | 0 (0) | - | 1 (2) | 33 |
| Pressure sensor and instrumented walkways | 1 (5) | 13 | 1 (2) | 38 |
| Medication adherence monitor | 1 (5) | 10 | 0 (0) | - |
| Geolocation monitor | 0 (0) | - | 1 (2) | 33 |
| Global Positioning System | 0 (0) | - | 1 (2) | 33 |
| Altimeter | 0 (0) | - | 1 (2) | 33 |