Table 2.
Summary of Corrected Visual Acuity by Visit (FAS Population).
| Parameter |
Descriptive
Statistics |
EYECRYL-SERT (N=41) | |||
|---|---|---|---|---|---|
| Screening |
PO 01
Month |
PO 03
Month |
PO 06
Month |
||
| Corrected Distance VA (Log MAR) | N | 40 | 40 | 39 | 40 |
| - | Mean (SD) | 0.74 (0.58) | 0.05 (0.07) | 0.04 (0.06) | 0.03 (0.04) |
| Median | 0.5 | 0.0 | 0.0 | 0.0 | |
| Min, Max | 0.2, 2.6 | 0.0, 0.2 | 0.0, 0.2 | 0.0, 0.1 | |
| p-value | - | <.0001 | <.0001 | <.0001 | |
| Corrected Distance VA Ref Range [n (%)] | 0-1 | 35 (85.37%) | 40 (97.56%) | 39 (95.12%) | 40 (97.56%) |
| - | >1 | 5 (12.20%) | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) |
| Corrected Intermediate VA (Log MAR) | N | - | 40 | 39 | 40 |
| - | Mean (SD) | - | 0.11 (0.08) | 0.10 (0.04) | 0.10 (0.04) |
| Median | - | 0.1 | 0.1 | 0.1 | |
| Min, Max | - | 0.0, 0.5 | 0.0, 0.2 | 0.0, 0.2 | |
| p-value | - | - | 1.0000 | 1.0000 | |
| Corrected Intermediate VA Ref Range [n (%)] |
0-1 | - | 40 (97.56%) | 39 (95.12%) | 40 (97.56%) |
| - | >1 | - | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) |
| Corrected Near VA (Log MAR) | N | - | 40 | 39 | 40 |
| - | Mean (SD) | - | 0.01 (0.06) | 0.01 (0.02) | 0.01 (0.02) |
| Median | - | 0.0 | 0.0 | 0.0 | |
| Min, Max | - | 0.0, 0.4 | 0.0, 0.1 | 0.0, 0.1 | |
| p-value | - | - | 1.0000 | 1.0000 | |
| Corrected Near VA Ref Range [n (%)] | 0-1 | - | 40 (97.56%) | 39 (95.12%) | 40 (97.56%) |
| - | >1 | - | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) |
|
Abbreviations: N=number of subjects in the specified treatment; n=number of subjects in the specified category; VA=visual acuity. '-'=Not applicable. Note 1: The given interval is inclusive of both values. Note 2: When screening, visit data was not available. We considered 'PO 01 Month' visit data as baseline. Note 3: All the parameters show non-normality hence p-values obtained by using Wilcoxon signed-rank test. | |||||