TABLE 2.
FUNCTIONAL CLASSIFICATION OF PBR EXPRESSION-REPRESSED GENES
| GenBank Accession No. | Genes |
|---|---|
| Cell surface markers/T-cell activation/T-cell development/cell adhesion | |
| D00749 | CD7 |
| M16336 | CD2 |
| M37815 | CD28 |
| L34657 | CD31 (PECAM 1) |
| M83554 | lymphocyte activation antigen CD30 |
| X64072 | integrin beta 2 (CD18) |
| M30894 | T-cell receptor Ti rearranged gamma-chain |
| J04164 | interferon-inducible protein 27-sep (IFI17) |
| M59807 | NK4 |
| M27396 | asparagine synthetase |
| D11327 | protein-tyrosine phosphatase (PTPN7) |
| M25280 | selectin L lymphocyte adhesion molecule 1 |
| U02609 | transducin (beta) like 3 (TBL3) |
| D78132 | Ras-related GTP binding protein (RHEB) |
| D25538 | adenylate cyclase |
| D89077 | Src-like adapter protein (SLAP) |
| D31797 | CD40 ligand (CD40L) |
| M55284 | protein kinase C-L (PKc eta) |
| Apoptosis | |
| X05908 | lipocortin I |
| AB006782 | galectin-9 |
| J04456 | galectin-1 |
| L06132 | VDAC |
| Immune responses | |
| X71874 | PSMB10 |
| M63262 | 5-lipoxygenase activating protein (FLAP) |
| U32849 | Hou |
| J04990 | cathepsin G |
| D32129 | HLA class I (HLA-A26) heavy chain |
| D49824 | HLA-B null allele |
| X75091 | HLA-DR associated protein II (PHAPII) |
| M94880 | MHC class I |
| S74221 | IK factor, downregulator of HLA II |
| M32334 | ICAM-2 |
| X57351 | interferon-induced transmembrane protein 2 (1-8D) (IFITM2) |
| M18737 | Hanukah factor serine protease (HuHF) granzyme A |
| Transcription/transduction | |
| J04088 | topoisomerase II |
| U63824 | transcription factor RTEF1 |
| D26156 | transcriptional activator hSNF2b |
| U29175 | transcriptional activator BRG1 |
| X17620 | Nm23 protein |
| Z35278 | RUNX3 |
| U35451 | heterochromatin protein p25 |
| X62153 | MCM3 |
| U41387 | DDX21, Gu protein |
| Z49194 | Oct binding factor |
| Y07604 | nucleoside-diphosphate kinase |
| L03532 | heterogeneous nuclear ribonucleoprotein M |
| L12723 | Hsp70 |
| U07563 | ribosomal RNA processing 4 (RRP4) |
| U08815 | splicesomal protein (SAP61) |
| X81625 | eukaryotic translation termination factor 1 (ETF1) |
| M34539 | FK506 binding protein (FKBP) |
| M88279 | immunophilin (FKBP52) |
| M80254 | cyclophilin isoform (hCyP3) |
| L15189 | mitochondrial HSP75 |
| Cytoskeleton organization | |
| D31883 | KIAA0059, actin binding LIM protein (ABLIM1) |
| M94345 | macrophage capping protein, CapG |
| U90878 | LIM domain protein CLP-36 |
| X82456 | LASP1 |
| L25081 | GTPase (rhoC) |
| M36284 | glycophorin |
| M95178 | alpha-actinin |
| Cell proliferation | |
| M34338 | spermidine synthase |
| S85655 | prohibitin |
| D50914 | block of proliferation BOP1 |
| U37022 | CDK4 |
| S78187 | CDC25 |
| X01060 | transferrin receptor |
| Miscellaneous | |
| M80244 | solute carrier family 7 member 5 (SLC7A5) |
| X16396 | NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase |
| D13643 | 3beta hydroxystrol delta-24-reductase (DHCR24) |
| M61832 | S-adenosylhomocystein hydrolase (AHCY) |
| U09510 | glycyl-tRNA synthetase |
| D31890 | lysyl-tRNA synthetase |
| U53225 | sorting nexin 1 (SNX1) |
| U53347 | neutral amino acid transporter B (SLC1A5) |
| X56494 | pyruvate kinase |
| U50743 | NA,K-ATPase gamma subunit |
| U30255 | phosphogluconate dehydrogenase (hPGDH) |
| Y00978 | dihydrolipoamide acetyltransferase (PDC-E2) |
| Unknown function | |
| D28137 | BST2 |
| M86934 | GS1 |
| D21853 | KIAA0111 |
| D63478 | KIAA0144 |
| D50915 | KIA0125 |