Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of modified unit B (13 and 14). Reagents and conditions: (a) 1) TsCl, DMAP, Et3N, CH2Cl2, rt, 4 h; 2) NaN3, DMF, 70 °C, overnight; (b) TsCl, Et3N, CH2Cl2, rt, overnight; (c) NaI, acetone, reflux, overnight; (d) TsCl, Et3N, CH2Cl2, rt, overnight; (e) NaI, acetone, reflux, overnight; (f) 6 or 9, K2CO3, DMF, 50 °C, overnight; (g) LiOH, H2O/MeOH/THF 1:1:1, rt, 2 h.
