Skip to main content
. 2018 Jun 5;14:1317–1348. doi: 10.3762/bjoc.14.113

Table 9.

Cu(OAc)2-catalyzed cycloaddition.

graphic file with name Beilstein_J_Org_Chem-14-1317-i084.jpg
entry R1 R3 reaction time (h) ratio 1,3:1,4 yield [%]
1 4-MeO-Ph Ph 5 <5:95 53
2 Ph COOEt 1 <5:95 93
3 4-MeO-Ph COOEt 2 <5:95 81
4 Ph n-Hex 3.5 <5:95 73
5 4-MeO-Ph n-Hex 3.5 <5:95 54
6 Ph cyclo-Hex 4 <5:95 100
7 4-MeO-Ph cyclo-Hex 2.5 <5:95 71
8 Ph cyclohex-1-enyl 2.5 <5:95 71
9 4-MeO-Ph cyclohex-1-enyl 2.5 <5:95 60
10 Ph cyclopropyl 4 <5:95 96
11 Ph thiophen-3-yl 2.5 <5:95 95
12 4-F-Ph COOEt 4 <5:95 95
13 Bn COOEt 4 <5:95 60