Table 2. . Major morbidity.
| Parameter | Estimate | 95% CI | p-value |
|---|---|---|---|
| Age (years) | |||
| 40–59 | 0.84 | 0.72–0.97 | 0.02 |
| 60–79 | 1.07 | 0.93–1.24 | 0.33 |
| 80+ | 1.39 | 1.07–1.80 | 0.01 |
| BMI (kg/m2) | |||
| – <20 | 0.80 | 0.59–1.08 | 0.14 |
| – >35 | 1.33 | 1.09–1.62 | 0.00 |
| Nonelective operation | 1.12 | 1.01–1.25 | 0.03 |
| Female sex | 0.87 | 0.80–0.94 | 0.00 |
| Inpatient | 2.60 | 0.97–6.98 | 0.06 |
| Nonwhite race | 1.05 | 0.93–1.19 | 0.44 |
| ASA class | |||
| (2) Mild disturbance | 0.70 | 0.53–0.93 | 0.01 |
| (3) Severe disturbance | 1.07 | 0.83–1.38 | 0.61 |
| (4/5) Life-threatening/moribound | 1.64 | 1.23–2.20 | 0.00 |
| Comorbidities | |||
| Bleeding disorders | 1.15 | 0.92–1.43 | 0.22 |
| Chronic obstructive pulmonary disorder | 1.23 | 1.05–1.45 | 0.01 |
| Congestive heart failure | 1.03 | 0.67–1.57 | 0.91 |
| Diabetes | 0.97 | 0.86–1.09 | 0.62 |
| Dialysis (current) | 1.02 | 0.62–1.65 | 0.95 |
| Disseminated cancer | 0.96 | 0.86–1.07 | 0.45 |
| Dyspnea | 1.00 | 0.83–1.19 | 0.97 |
| Functional dependence | 1.30 | 1.11–1.51 | 0.00 |
| Hypertension | 1.00 | 0.92–1.10 | 0.92 |
| Renal failure | 2.37 | 1.29–4.35 | 0.01 |
| Smoking | 0.99 | 0.89–1.10 | 0.80 |
| SIRS/sepsis/septic shock | 1.44 | 1.22–1.71 | <0.0001 |
| Steroids (for chronic condition) | 1.34 | 1.21–1.49 | <0.0001 |
| Transfusion (preoperative) | 1.43 | 0.92–2.24 | 0.11 |
| Ventilator dependent | 1.79 | 1.35–2.38 | <0.0001 |
| Weight loss | 1.25 | 0.98–1.60 | 0.08 |
| Wound infection/open wound (preoperative) | 1.87 | 1.42–2.48 | <0.0001 |
ASA: American Society of Anesthesiologist; SIRS: Systemic inflammatory response syndrome.