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. 2018 May 16;14:1051–1086. doi: 10.3762/bjoc.14.93

Figure 2.

Figure 2

(a) Portions of MATα1–MATα2 are shown contacting the minor groove of the DNA substrate. Key arginine residues within this region facilitate the interaction (PDB ID# 1AKH) [25]; (b) Figure shows DNA bound to λ repressor protein. Alpha helices of the protein dimers recognize specific sequences within the DNA major groove (PDB ID# 1LMB) [26]; (c) The MetJ dimer β sheet contacts the DNA ligand major groove via side chains on the face of the β sheet (PDB ID# 1CMA) [27].