Table 2.

Summary of lacl mutations in double hTF/hMGMT × lacl and single lacl transgenic mice

Mutation	Lacl	LC22l/lacl	LC26l/lacl	Transgenic total
GC→AT	18 (9)*	10 (6)	7 (4)	17 (10)
GC→TA	5 (2)	8 (4)	10 (4)	18 (8)
Other BPS†	4	3	2	5
Double BPS	1	6	4	10
Insertion/deletion	3	6	7	13
Multiple mutations	1	1	2	3
Total mutations	32	34	32	66

^*Numbers in parentheses indicate the number of mutations at CpG sites. 

^† BPS, base pair substitution.