Table 1. Composite and transposed C/D box sRNAs.
C/D box sRNA | Type | D′ guide | D guide |
---|---|---|---|
Pca sR12/45 | Composite | Shared with sR45 family D′ guide | Shared with sR12 family D guide |
Pca sR103/109 | Composite | Shared with sR103 family D′ guide | Shared with sR109 family D guide |
Pca sR26a | Transposed | Shared with sR26 family D guide | Not shared |
Pae sR57a | Transposed | Not shared | Shared with sR57 family D guide |
Pca sR57b | Transposed | Shared with sR57 family D guide | Not shared |
Par and Pog sR13a | Transposed | Shared with sR13 family D guide | Not shared |
Two unusual types of sRNAs (composite and transposed) were identified. Composite sRNAs have a D guide that shows sequence similarity to a guide in one sRNA family, whereas the D′ guide shows sequence similarity to a guide from a second sRNA family. These are given both family numbers separated by a forward slash (/). Transposed sRNAs have either a D guide that is shared with the D′ guide of the defining family, or vice versa, a D′ guide that is shared with the D guide of another family. Transposed sRNAs are identified with the number of the defining family followed by a lower-case a or b. The Pae sR57a is considered as a transposed sRNA since the D′ guide normally associated with the sR57 is not present (to view these sRNA sequences, see http://lowelab.ucsc.edu/snoRNAdb/).