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. 2018 May 4;46(11):5861–5874. doi: 10.1093/nar/gky346

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — Analysis of the domain movement using domain motion analysis. (A and C) Side view and (B and D) top view of the principal axes of each domain in the open conformation (near-cognate tRNA) and closed conformation (cognate tRNA and C₄), respectively. Axes are shown for EF-Tu (red) and the 16S domains I (blue), III major (green) and III minor (pink). The axes of the reference domain (23S) is highlighted in gray. The small green arrow indicates the axis of rotation going form the near-cognate to the cognate case. Cartoon model representation of the domains are available in Supplementary Figure S3.