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. 2018 Mar 13;46(11):e65. doi: 10.1093/nar/gky185

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — (A) Sequence of 18-labeled RNA ONs 17a′, 19a′ and 20a′ and custom DNA ONs. RNA ONs were hybridized to DNA ONs such that the emissive nucleoside was placed opposite to complementary base and mismatched bases. For example, hybridization of RNA ON 17a′ with DNA ONs 17A, 17T, 17G and 17C will place 18 opposite to complementary base dA and mismatched bases dT, dG and dC, respectively. (B−D) Emission spectra of RNA ONs and corresponding duplexes.