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. 2018 Mar 29;46(11):5441–5454. doi: 10.1093/nar/gky234

Table 1. (A and B) Transcription factors (TFs) exhibiting similar genomic distributions to that of LSD1. LSD1 peaks were divided into two groups, LSD1-bound promoters (<TSS ± 1 kb) (A) and outside of promoters (>TSS ± 1 kb) (B). An extensive comparison with publicly available datasets was conducted for each group, using the ChIP-Atlas (http://chip-atlas.org/). Top 10 rankings are shown.

Rank ID Antigen Cell Num of peaks Overlaps / LSD1 Overlaps / random Fold enrichment P-value Q-value
(A) TFs similarly distributed with LSD1 (<TSS ± 1 kb)
1 SRX3206550 Brd4 Muscle, Skeletal 5236 4424/11268 27/11268 163.852 <1.0 × 10−324 <1.0 × 10−324
2 SRX3206547 Brd4 Muscle, Skeletal 6926 5690/11268 39/11268 145.897 <1.0 × 10−324 <1.0 × 10−324
3 SRX3206545 Brd4 Muscle, Skeletal 9561 7152/11268 50/11268 143.04 <1.0 × 10−324 <1.0 × 10−324
4 SRX142538 E2f4 C2C12 2379 1628/11268 13/11268 125.231 <1.0 × 10−324 <1.0 × 10−324
5 SRX522661 Sin3a C2C12 2230 1845/11268 15/11268 123 <1.0 × 10−324 <1.0 × 10−324
6 SRX956815 Six4 C2C12 4850 3510/11268 29/11268 121.034 <1.0 × 10−324 <1.0 × 10−324
7 SRX344972 Sin3a C2C12 1797 1405/11268 12/11268 117.083 <1.0 × 10−324 <1.0 × 10−324
8 SRX150192 Hdac1 Myoblasts 2823 1217/11268 11/11268 110.636 <1.0 × 10−324 <1.0 × 10−324
9 SRX142525 Max C2C12 6364 2661/11268 30/11268 88.7 <1.0 × 10−324 <1.0 × 10−324
10 SRX142526 Rest C2C12 5494 1466/11268 17/11268 86.2353 <1.0 × 10−324 <1.0 × 10−324
(B) TFs similarly distributed with LSD1 (>TSS ± 1 kb)
1 SRX770038 Myod1 C2C12 4298 3786/40746 60/40746 63.1 <1.0 × 10−324 <1.0 × 10−324
2 SRX142533 Fosl1 C2C12 3696 2664/40746 45/40746 59.2 <1.0 × 10−324 <1.0 × 10−324
3 SRX328690 Myod1 C2C12 10980 8705/40746 153/40746 56.8954 <1.0 × 10−324 <1.0 × 10−324
4 SRX142529 Tcf12 C2C12 7817 6126/40746 112/40746 54.6964 <1.0 × 10−324 <1.0 × 10−324
5 SRX142537 Myod1 C2C12 12521 8722/40746 166/40746 52.5422 <1.0 × 10−324 <1.0 × 10−324
6 SRX142515 Myog C2C12 5718 4341/40746 84/40746 51.6786 <1.0 × 10−324 <1.0 × 10−324
7 SRX142516 Myod1 C2C12 3446 2568/40746 50/40746 51.36 <1.0 × 10−324 <1.0 × 10−324
8 SRX1817465 Tead4 C2C12 1697 1478/40746 29/40746 50.9655 <1.0 × 10−324 <1.0 × 10−324
9 SRX039346 Epitope tags C2C12 3133 1462/40746 29/40746 50.4138 <1.0 × 10−324 <1.0 × 10−324
10 SRX213538 Mef2d C2C12 3551 1840/40746 37/40746 49.7297 <1.0 × 10−324 <1.0 × 10−324