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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2017 Dec 14;53(1):83–98. doi: 10.1080/10409238.2017.1409191

Figure 4. Divergence in APT1•ML348 and APT2•ML349 structures.

Figure 4

Blue regions signify divergence between APT1 and APT2. The inhibitor selectivity filter APT1-L176M and APT2-M178L is shown in grey sticks in the β8/α4 region. Adapted with permission from (Won et al. 2016). A color version of the figure is available online.