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. 2018 Mar 14;33(1):651–656. doi: 10.1080/14756366.2018.1444608

Table 4.

Anti-proliferative activities of new compounds in vitro

  IC50 (μM)a
Compounds Ramos b Raji b RPMI-8226 b SU-DHL-6 c
12d 1.34 9.81 0.44 3.23
14b 1.34 0.81 8.66 1.04
14c ND ND ND 1.49
1 >10 9.95 5.49 0.65
SAHA 0.52 0.97 0.66 ND

aThe IC50 values are shown as the mean for at least two experiments.

bAnti-proliferative activities were determined by(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium (MTT) reduction method.

cAnti-proliferative activities were determined by CCK-8 method.

ND: not detected.