Table 4.
IC50 (μM)a |
||||
---|---|---|---|---|
Compounds | Ramos b | Raji b | RPMI-8226 b | SU-DHL-6 c |
12d | 1.34 | 9.81 | 0.44 | 3.23 |
14b | 1.34 | 0.81 | 8.66 | 1.04 |
14c | ND | ND | ND | 1.49 |
1 | >10 | 9.95 | 5.49 | 0.65 |
SAHA | 0.52 | 0.97 | 0.66 | ND |
aThe IC50 values are shown as the mean for at least two experiments.
bAnti-proliferative activities were determined by(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium (MTT) reduction method.
cAnti-proliferative activities were determined by CCK-8 method.
ND: not detected.