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Permeability (Pe×10−6 cm s−1) in the PAMPA-BBB assay for nine commercial drugs, used in the experiment validation.
| Commercial drugs | Bibla | PBS:EtOH(70:30)b |
|---|---|---|
| Testosterone | 17 | 16.44 |
| Verapamil | 16 | 16.88 |
| beta-Estradiol | 12 | 11.93 |
| Progesterone | 9.3 | 5.34 |
| Corticosterone | 5.1 | 4.06 |
| Piroxicam | 2.5 | 1.42 |
| Hydrocortisone | 1.9 | 1.86 |
| Ofloxacin | 0.8 | 0.47 |
| Dopamine | 0.2 | 0.17 |
Taken from Ref.49
Data are the mean ± SD of three independent experiments.
