Table 3.

IC₅₀ values of AAZ and 1–4 on hydratase and esterase activity of hCA-I and hCA-II and K_i values of hCA-I and hCA-II.

	Hydratase IC50 (μM)		Esterase IC50 (μM)		Ki(μM)
Inhibitor	hCA-I	hCA-II	hCA-I	hCA-II	hCA-I	hCA-II
AAZ	3.3000	2.4000	4.6000	3.9000	2.8000	2.1000
1	1.4000	0.9000	2.8000	5.6000	1.1000	5.3000
2	2.4000	0.0625	0.0820	0.0190	0.1460	0.0960
3	0.0600	0.0340	0.1450	0.0900	0.1480	0.0724
4	0.0520	0.0420	0.3400	0.0920	0.3930	0.0980