Table 3.
The effect of compounds on indomethacin-induced gastric mucosal lesions (mean ± SE).
| Treatment | Dose (mg/kg, i.p.) | Ulcer index |
|---|---|---|
| Control (indomethacin) | 30 | 35.66 ± 1.05 |
| Ranitidine (standard) | 50 | 8.50 ± 0.56*** |
| 3 | 12.5 | 29.83 ± 1.66* |
| 3 | 25 | 20.50 ± 1.52*** |
| 3 | 50 | 12.66 ± 1.28*** |
| 8 | 12.5 | 33.00 ± 1.52 |
| 8 | 25 | 29.50 ± 1.58* |
| 8 | 50 | 28.66 ± 1.45** |
| 11 | 12.5 | 33.00 ± 1.03 |
| 11 | 25 | 30.66 ± 1.28* |
| 11 | 50 | 28.33 ± 1.78** |
| 15 | 12.5 | 26.33 ± 1.30*** |
| 15 | 25 | 21.50 ± 1.33*** |
| 15 | 50 | 14.50 ± 1.64*** |
Six rats were used in each group.
p < .05,
p < .01,
p < .001 vs. control (indomethacin only) group, Student’s t-test.