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. 2018 May 24;33(1):978–988. doi: 10.1080/14756366.2018.1474212

Table 7.

The effect of compounds on the levels of MDA, NP-SH and TP in stomach tissue induced by 80% ethanol (mean ± SE).

Treatment Dose (mg/kg, i.p.) MDA (nmol/g) NP-SH (nmol/g) Total protein (g/l)
Control (normal) 1.14 ± 0.06 5.03 ± 0.10 122.55 ± 3.23
80% EtOH 1 ml 7.42 ± 0.30***,a 3.22 ± 0.20***,a 47.50 ± 2.08***,a
Ranitidine (standard) 50 1.65 ± 0.02***,b 4.24 ± 0.15**,b 104.59 ± 1.59***,b
3 12.5 4.47 ± 0.44***,b 3.15 ± 0.20b 58.68 ± 3.19*,b
3 25 3.07 ± 0.16***,b 4.23 ± 0.23**,b 74.65 ± 3.79***,b
3 50 1.95 ± 0.05***,b 4.56 ± 0.17***,b 95.80 ± 1.51***,b
8 12.5 6.63 ± 0.26b 3.49 ± 0.16b 45.90 ± 1.14b
8 25 4.83 ± 0.24***,b 3.61 ± 0.12b 55.88 ± 1.71*,b
8 50 3.75 ± 0.07***b 4.61 ± 0.27**,b 66.26 ± 1.47***
11 12.5 5.16 ± 0.22***,b 2.93 ± 0.11b 53.89 ± 1.48*,b
11 25 3.99 ± 0.17***,b 3.40 ± 0.18b 64.27 ± 2.08***,b
11 50 3.36 ± 0.08***,b 4.35 ± 0.11***,b 72.25 ± 1.43***,b
15 12.5 3.51 ± 0.08***,b 3.38 ± 0.07b 71.45 ± 1.43***,b
15 25 2.72 ± 0.10***,b 4.29 ± 0.24**,b 81.43 ± 3.65***,b
15 50 1.90 ± 0.06***,b 4.92 ± 0.30***,b 96.60 ± 1.18***,b

Six rats were used in each groups,

*

p < .05,

**

p < .01,

***

p < .001 vs. control (80% ethanol only) group, Student’s t-test.

a

As compared to the control group.

b

As compared to 80% ethanol only group.