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. 2017 Aug 4;32(1):1102–1110. doi: 10.1080/14756366.2017.1355793

Table 1.

Catabolic rate of serum CN1 in the presence of inhibitors (n = 5).

  Vmax (µmol/mg/h) Km (mM) Efficiency (Vmax/Km)
Control 4.2 ± 0.4 0.8 ± 0.1 5.2 ± 0.2
Cysteine (1 mM) 1.8 ± 0.2* 1.0 ± 0.2 1.6 ± 0.2*
N-acetylcysteine (1 mM) 2.4 ± 0.2* 1.1 ± 0.3 2.0 ± 0.3*
GSH (1 mM) 2.9 ± 0.4* 0.9 ± 0.2 3.2 ± 0.4*
GSSG (1 mM) 4.1 ± 0.5 0.9 ± 0.3 4.6 ± 0.4
l-Glutamic acid (1 mM) 4.2 ± 0.5 0.8 ± 0.2 5.2 ± 0.3
Glycine (1 mM) 4.1 ± 0.4 0.7 ± 0.3 5.8 ± 0.4

Efficiency of recombinant CN1 activity were calculated by the ratio of Vmax and Km.

*

p < .05 compared to control.