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% inhibitory effect of the compounds on kinase activities.
| Compd No. | % inhibition of 10 μM |
|||
|---|---|---|---|---|
| EGFR | HER2 | HER4 | cSrc | |
| Staurosporinea | 94 | 81 | 100 | 100 |
| 2b | 0 | 1 | 5 | 4 |
| 3b | 0 | 0 | 3 | 3 |
| 6a | 6 | 1 | 5 | 5 |
| 7a | 0 | 0 | 4 | 1 |
| 7b | 1 | 0 | 3 | 3 |
| 8a | 6 | 0 | 10 | 4 |
aStaurosporine used in 1 μM concentration.
