Table 2.
1H NMR data and main fragments in E.I. mass spectrometry of derivatives EMAC II (i–m).
| Compound | 1H NMR δ (ppm) |
|---|---|
| EMAC II i | 1H-NMR: (300 MHz, CDCl3) δH 2.38 (s, 3H, CH3), 3.23 (dd, 1H, Jab 16.5, Jax 7.8, CH2, isoxazole), 3.76 (dd, 1H, Jab 16.5, Jbx 10.1, CH2, isoxazole), 5.59 (dd, 1H, Jbx 10.8, Jax 8.1, CH, isoxazole), 7.21 (d, 2H, J 7.8, CH, arom.), 7.33 (m, 4H, CH, arom.), 7.57 (2H, d, J 8.1, CH, arom.). |
| EMAC II j | 1H-NMR: (300 MHz, CDCl3) δH 2.37 (s, 3H, CH3), 2.43 (s, 3H, CH3), 3.30 (dd, 1H, Jab 16.5, Jax 8.3, CH2, isoxazole), 3.72 (dd, 1H, Jab 16.5, Jbx 10.8, CH2, isoxazole), 5.66 (dd, 1H, Jbx 10.8, Jax 8.3, CH, isoxazole), 7.16–7.29 (m, 6H, CH, arom.), 7.57 (d, 2H, J 8.3, CH, arom.). |
| EMAC II k | 1H-NMR: (300 MHz, CDCl3) δH 2.35 (s, 3H, CH3), 3.27 (dd, 1H, Jab 16.7, Jax 8.0, CH2, isoxazole), 3.74 (dd, 1H, Jab 16.5, Jbx 10.7, CH2, isoxazole), 5.69 (dd, 1H, Jbx 10.7, Jax 8.3, CH, isoxazole), 7.04 (t, 2H, J 8.3, CH, arom.), 7.21 (d, 2H, J 8.1, CH, 4-CH3-phenyl), 7.36 (dd, 2H, CH, J 8.3/5.3, arom.), 7.56 (d, 2H, J 8.2, CH, 4-CH3-phenyl). |
| EMAC II l | 1H-NMR: (300 MHz, CDCl3) δH 2.38 (s, 3H, CH3), 3.27 (dd, 1H, Jab 16.7, Jax 7.8, CH2, isoxazole), 3.78 (dd, 1H, Jab 16.4, Jbx 10.8, CH2, isoxazole), 5.67 (dd, 1H, Jbx 10.8, Jax 7.8, CH, isoxazole), 7.21 (m, 3H, CH, arom.), 7.44 (d, 1H, J 8.2, CH, arom.), m, 7.49 (d, 1H, J 1.2, CH, arom.), 7.56 (d, 2H, J 8.1, CH, arom.). |
| EMAC II m | 1H-NMR: (300 MHz, CDCl3) δH 2.38 (s, 3H, CH3), 3.30 (dd, 1H, Jab 16.7, Jax 7.8, CH2, isoxazole), 3.71 (dd, 1H, Jab 16.5, Jbx 10.6, CH2, isoxazole), 3.80 (s, 3H, OCH3), 5.66 (dd, 1H, Jbx 10.5, Jax 8.6, CH, isoxazole), 6.89 (d, 2H, J 8.3, CH, arom.), 7.21 (d, 2H, J 8.2, CH, 4-CH3-phenyl), 7.31 (d, 2H, J 8.7, CH, arom.), 7.58 (d, 2H, J 8.2, CH, 4-CH3-phenyl). |