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. 2018 Apr 25;33(1):833–841. doi: 10.1080/14756366.2018.1461856

Figure 8.

Figure 8.

ZJ01 induced the Nrf2 nuclear accumulation and inhibited LPS-induced inflammatory cytokines production of left ventricular cells in vivo. (A) C57BL/6 mice were treated intraperitoneally with different concentrations of ZJ01 for 12 h. The nuclear and non-nuclear Nrf2 protein levels of left ventricular cells were determined by Western blotting technology. (B) C57BL/6 mice were treated intraperitoneally with 4 mg/kg of LPS and then with 5 mg/kg ZJ01 for 12 h. RT-PCR analysis of the expression of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. **p < .01 vs. control, #p < .05 vs. LPS group. n = 3.