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. 2017 Mar 8;32(1):659–671. doi: 10.1080/14756366.2016.1265521

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© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Scheme 1. — The process of AChE carbamoylation and decarbamoylation.^a^aEH is the free enzyme, AB is the inhibitor, EH · · · AB is the non-covalent complex and EA is the carbamylated enzyme. k_i is inhibit constant and k₃ is dissociation constant.