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Multialignment of the TweCAδ amino acid sequence with those of bacterial (HpylCA, α-CA from Helicobacter pylori, SspCA, α-CA from Sulfurihydrogenibium yellowstonensis) and human (hCA I and II) α-class enzymes. The zinc ligands of the α-CAs and the putative zinc ligands of TweCAδ are evidenced in red, whereas amino acid residues involved in the catalytic inhibition/mechanism (e.g. His64 and Asp106, hCA I numbering) are shown in green and blue, respectively.
