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. 2018 Mar 7;33(1):560–566. doi: 10.1080/14756366.2018.1441839

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Anti-inflammatory activity of F-81, administered i.p. once a day over 3 days, in the prevention mouse model of the TNBS-induced colitis. Macroscopic score (Panel A), inflammation area (Panel B), ulcer score (Panel C), colon thickness (Panel D), MPO activity (Panel E), colon width (Panel F), and colon length (Panel G). Statistical significance was assessed using one-way ANOVA and post hoc multiple comparison Student–Newman–Keuls test. ***p < .001, as compared with controls. ^#p < .05, ^###p < .001, vs. TNBS-treated animals. Data represent mean ± SEM of eight mice per group.