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. 2018 May 3;33(1):879–889. doi: 10.1080/14756366.2018.1465055

Scheme 1.

Scheme 1.

Synthesis route of 3-methylbenzo[d]thiazol-methylquinolinium derivatives. Reagents and conditions: (a) iodomethane, tetramethylene sulfone, 50 °C, reflux; (b) iodomethane, absolute ethanol, 80 °C, reflux; (c) NaHCO3, methanol, room temperature; (d) aromatic aldehydes, 4-methylpiperidine, n-butanol, 135 °C, reflux.