Table 2.

In vitro cytotoxicity of target compounds

	IC50 ± SDa (μM)
compd	HCT116	MCF7	Hela	H1299	B16
3a	0.214 ± 0.003	0.340 ± 0.003	0.337 ± 0.054	0.331 ± 0.091	0.272 ± 0.010
3b	0.088 ± 0.004	0.069 ± 0.009	0.122 ± 0.017	0.109 ± 0.002	0.104 ± 0.011
3c	0.093 ± 0.002	0.084 ± 0.003	0.251 ± 0.059	0.144 ± 0.013	0.108 ± 0.010
3d	0.597 ± 0.014	>10	>10	0.830 ± 0.162	0.787 ± 0.203
3e	0.742 ± 0.045	1.092 ± 0.421	3.456 ± 3.188	1.019 ± 0.111	0.709 ± 0.027
3f	0.189 ± 0.035	0.194 ± 0.055	0.412 ± 0.018	0.206 ± 0.018	0.189 ± 0.006
3g	0.164 ± 0.003	0.638 ± 0.020	0.298 ± 0.053	0.247 ± 0.015	0.159 ± 0.002
3h	0.374 ± 0.015	0.234 ± 0.045	1.126 ± 0.080	0.306 ± 0.008	0.317 ± 0.022
Shikonin	1.060 ± 0.182	2.405 ± 0.346	0.813 ± 0.081	0.954 ± 0.186	1.220 ± 0.155