Table 4.

Metal content in the liver of male Wistar rats.

Groups	Exposure (days)	Metal
		Cd	Cu	Fe	Zn	Mg	Se
		Control	0	/	3.3 ± 0.28	66.0 ± 12.12	37.5 ± 4.44	240.2 ± 17.35	15.2 ± 0.39
Cd	1	55.8 ± 5.48	5.6 ± 0.93**	69.4 ± 9.53	54.4 ± 8.68*	240.5 ± 22.62	41.9 ± 1.95***
	3	54.22 ± 9.43	5.3 ± 0.43**	58.5 ± 7.32	58.1 ± 5.47**	240.0 ± 11.21	32.2 ± 4.97***
	10	57.5 ± 8.68	6.3 ± 0.38***	77.3 ± 10.21	78.1 ± 6.66***	261.9 ± 48.31	28.4 ± 1.13***
	21	107.3 ± 5.93 μ***	8.4 ± 1.64***	87.0 ± 7.03***	96.7 ± 12.59***	239.7 ± 31.11	22.6 ± 2.44*
	42	166.5 ± 26.3 μ***	8.7 ± 1.19***	138.5 ± 11.95***	96.3 ± 16.94***	242.0 ± 29.96	/
DSF	1	/	3.9 ± 0.62	64.2 ± 11.65	42.5 ± 3.53	242.8 ± 19.45	18.5 ± 0.52
	3	/	5.6 ± 0.97**	57.5 ± 9.50	67.9 ± 11.44***	244.4 ± 24.41	34.9 ± 6.44***
	10	/	5.7 ± 1.18**	62.1 ± 6.87	69.3 ± 12.38***	233.8 ± 34.33	43.6 ± 7.78***
	21	/	9.0 ± 1.74***	100.1 ± 14.31***	65.6 ± 6.39**	219.7 ± 16.80	44.8 ± 8.13***
Cd + DSF	1	133.0 ± 19.46 μ***	5.7 ± 0.73**	94.7 ± 13.34***	108.6 ± 7.31***	241.6 ± 16.61	22.0 ± 0.61*
	3	106.6 ± 13.8 μ***	13.9 ± 1.61***	94.4 ± 6.23***	114.3 ± 11.23***	230.6 ± 7.72	22.3 ± 3.14*
	10	152.2 ± 29.48 μ***	9.4 ± 1.48***	102.4 ± 10.68***	145.5 ± 9.87***	241.2 ± 14.37	23.3 ± 2.03*
	21	235.3 ± 11.46 μ***	5.6 ± 0.29**	197.6 ± 11.50***	156.1 ± 14.21***	242.5 ± 31.55	24.2 ± 0.99**

Significances between experimental groups in essential metal content determination refer to comparison between the experimental groups and the control group (intact animals); Significances between experimental groups in Cd content determination refer to comparison between the experimental groups and Cd1 subgroup (μ); Level of significance is labeled as follows: *(p < 0.01), **(p < 0.001), ***(p < 0.0001); Values are expressed as mean ± standard deviation of six separate analyses (n = 6); 21-day period refers to administration of DSF for 21 days in the combined treatment; Units of metals are expressed as μg/g tissue for Cd, Cu, Fe, Zn, Mg and ng/g tissue for Se.