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. 2016 Oct 23;32(1):113–118. doi: 10.1080/14756366.2016.1238364

Table 1.

Inhibition of human CDC25 isoforms by quinones and quinone-like compounds 1, and 35.

  IC50 (μM)*
Mol CDC25A CDC25B CDC25C
1 2.64 ± 0.62 6.99 ± 0.21 5.72 ± 0.27
3 3.19 ± 1.02 11.13 ± 1.01 5.41 ± 0.52
4 3.73 ± 1.53 18.20 ± 1.68 9.43 ± 1.25
5 2.53 ± 0.23 7.46 ± 2.17 5.76 ± 0.42
*

Values are expressed as mean of triplicates ± standard deviation (SD).