Table 4.
Data results of ME and RE, obtained in human and rat plasma samples, and evaluation of LEDA performances.
| Human plasma |
Rat plasma |
|||||
|---|---|---|---|---|---|---|
| Compound | ME% | RE% | ME% | RE% | LEDA Purity% |
SD% |
| ISTD | 98 | 95 | 96 | 100 | n.d. | n.d. |
| 1A | 93 | 94 | 74 | 88 | 100 | 4.0 |
| 1B | 84 | 97 | 71 | 88 | 91 | 1.2 |
| 2A | 84 | 91 | 78 | 96 | 96 | 2.8 |
| 2B | 95 | 96 | 98 | 98 | 94 | 2.5 |
| 3A | 97 | 97 | 97 | 93 | 100 | 1.0 |
| 3B | 94 | 94 | 94 | 98 | 100 | 1.1 |
| 4A | 78 | 86 | 93 | 81 | 100 | 0.1 |
| 4B | 67 | 95 | 82 | 98 | 100 | 0.7 |
| 5A | 87 | 94 | 72 | 85 | 99 | 1.3 |
| 5B | 94 | 95 | 87 | 95 | 100 | 1.0 |
| 6A | 97 | 92 | 100 | 92 | 96 | 0.2 |
| 6B | 98 | 78 | 97 | 75 | 100 | 3.5 |
| 7A | 97 | 96 | 98 | 97 | 100 | 1.7 |
| 7B | 96 | 96 | 98 | 99 | 92 | 0.9 |
| 8A | 100 | 95 | 99 | 100 | 100 | 0.8 |
| 8B | 95 | 89 | 95 | 87 | 100 | 0.9 |
n.d.: not determined.