Table 2.
Summary of ANCOVAs examining differences between cases and controls on cluster methylation and NAc MID task percent signal change (β).
| Alcohol-Dependent Patients (n = 45) | Healthy Controls (n = 45) | F | P-Value | Eta-squared | |
|---|---|---|---|---|---|
| Percent Methylation | |||||
| Cluster A | 9.11 (8.53, 9.69) | 9.42 (8.84, 9.99) | .510 | .477 | .006 |
| Cluster B | 8.38 (7.89, 8.87) | 8.44 (7.95, 8.93) | .026 | .872 | .000 |
| Cluster C | 62.35 (61.25, 63.44) | 61.86 (60.75, 62.97) | .349 | .556 | .004 |
| Cluster D | 89.22 (88.92, 89.53) | 89.17 (88.86, 89.48) | .053 | .819 | .001 |
| Cluster E | 77.96 (77.35, 78.57) | 78.22 (77.61, 78.83) | .338 | .563 | .004 |
|
| |||||
| NAc Activation | |||||
| High Reward | .172 (.038, .307) | -.059 (-.195, .077) | 5.33 | .023 | .059 |
| Low Reward | -.031(-.153, .091) | -.220 (-.343 -.096) | 4.27 | .042 | .048 |
| High Loss | .078 (-.037, .192) | -.160 (-.275, -.044) | 7.74 | .007 | .083 |
| Low Loss | -.026 (-.140, .088) | -.224 (-.338, -.110) | 5.48 | .022 | .061 |
Note. Adjusted means and confidence intervals.