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. 2018 Jun 20;13(6):e0199323. doi: 10.1371/journal.pone.0199323

Fig 1. Phylogenetic analysis of available CBV sequences.

Fig 1

Polyprotein sequences returned from Genbank for the terms “coxsackievirus B”; “coxsackie B virus”; “CBV”; “CVB”, listed in Table 1, were aligned using ClustalW pairwise alignment in Mega6. Genetic similarity between sequences and serotype clades in this alignment was assessed by generation of a maximum-likelihood phylogenetic tree. Sequences for CBV1 (10- highlighted in blue), CBV2 (7- light blue), CBV3 (29- red), CBV4 (25-purple), CBV5 (15-orange) and CBV6 (6- green) all clustered together with sequences for the same serotype, as would be expected from their labelling on Genbank.