Table 3. Cross-validation of SHG B-index to predict Brunt fibrosis stage.
| NAFLD Fibrosis Group | Brunt fibrosis stage | SHG B-index cut-off | Sens | Spec | +LR | -LR | PPV | NPV |
|---|---|---|---|---|---|---|---|---|
| Mild fibrosis | 0 vs 1/2/3/4 | 1.18 | 65.6% | 84.2% | 4.15 | 0.41 | 93.2% | 41.0% |
| Significant fibrosis | 0/1 vs 2/3/4 | 1.33 | 84.6% | 86.4% | 6.22 | 0.18 | 86.8% | 86.7% |
| Bridging fibrosis | 0/1/2 vs 3/4 | 1.76 | 87.5% | 98.0% | 43.75 | 0.13 | 96.6% | 92.6% |
| Cirrhosis | 0/1/2/3 vs 4 | 2.76 | 83.8% | 89.2% | 7.71 | 0.19 | 66.7% | 93.6% |
Sens = Sensitivity, Spec = Specificity
+LR = Positive likelihood ratio, -LR = Negative likelihood ratio
PPV = Positive Predictive Value, NPV = Negative Predictive Value