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. 2018 Jun 20;13(6):e0199473. doi: 10.1371/journal.pone.0199473

Fig 4. Cas9 RNPs treatment for depletion of multiple gRNAs.

Fig 4

(A) Targeted deep sequencing analysis of the kinase-depleted GeCKOv2 A library. The scatter plots showed that all 81 gRNAs that targeted 27 human kinase genes were depleted in the kinase-depleted compared with the wild-type library. (B) Relative gRNA quantities were calculated from the deep sequencing data. Numerical data are presented in S3 Table.