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. 2018 May 29;7:e33092. doi: 10.7554/eLife.33092

Figure 10. Spontaneous firing rate is regulated by Rem2 in vivo.

Figure 10.

A) Representative extracellular multi-unit voltage traces from L2/3 neurons in binocular visual cortex (V1b) of wildtype (top) and Rem2-/- (bottom) typically reared mice sampled during the peak (P28, left) and late (P34, right) visual critical period. (B) Average spontaneous multiunit firing rate of L2/3 V1b neurons sampled from anesthetized wildtype and Rem2-/- mice during the peak (Right, P28 WT, black, n = 24 sites recorded from 4 mice; P28 Rem2-/-, purple, n = 29 sites recorded from 5 mice) and late (Left, P34 WT, black, n = 14 sites sampled from 3 mice; P34 Rem2-/-, blue, n = 13 sites sampled from 3 mice) visual critical period. Each small circle represents one recording site. Orange circles and error bars are mean ± SEM. *p<0.0153 by Kruskal-Wallis test.