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. 2018 May 29;7:e33092. doi: 10.7554/eLife.33092

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© 2018, Moore et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 9. — (A) Experimental timeline of acute, viral-mediated Rem2 deletion in Rem2^flx/flx mice with 2 days monocular deprivation (MD). V.I., virus injection. (B) Examples of spontaneous firing recorded in GFP⁺ layer 2/3 pyramidal neurons in Rem2^flx/flx + AAV GFP (top left, n = 22), Rem2^flx/flx + AAV GFP+2 d MD (bottom left, n = 17), Rem2^flx/flx + AAV GFP-Cre (top right, n = 17), and Rem2^flx/flx + AAV GFP-Cre+2 d MD (bottom right, n = 20). (C) Average firing rate measured in layer 2/3 pyramidal neurons. Data is presented as individual data points, with the horizontal bar denoting average. N = 4 animals per condition. Error bars represent S.E.M. *p<0.05, by two-way ANOVA with Tukey post-hoc.