Table 2. Passive membrane properties of layer 2/3 neurons in visual cortex.
Experimental condition | VR (mV) | RIN (GΩ) | CM (pF) | Tau (ms) |
---|---|---|---|---|
WT TR | −68.01 ± 0.43 | 95.09 ± 1.56 | 113.98 ± 1.70 | 10.78 ± 0.21 |
WT 2d MD | −66.78 ± 0.38 | 96.46 ± 2.11 | 108.84 ± 2.48 | 10.12 ± 0.15 |
Rem2-/- TR | −64.98 ± 0.26 | 111.61 ± 1.80 | 105.50 ± 1.95 | 11.44 ± 0.16 |
Rem2-/- 2d MD | −68.38 ± 0.38# | 100.94 ± 2.25 | 109.70 ± 2.72 | 10.79 ± 0.27 |
WT TR | −64.22 ± 0.23 | 104.15 ± 1.64 | 118.55 ± 1.97 | 12.03 ± 0.15 |
WT 6d MD | −64.92 ± 0.19 | 109.38 ± 1.10 | 119.94 ± 1.46 | 10.77 ± 0.10# |
Rem2-/- TR | −63.39 ± 0.43 | 112.06 ± 1.62 | 124.80 ± 2.15 | 13.86 ± 0.29 |
Rem2-/- 6d MD | −64.38 ± 0.19 | 99.61 ± 1.34 | 125.31 ± 1.61 | 11.96 ± 0.15 |
4 days post infection Rem2flx/flx + AAV-GFP |
−67.48 ± 0.54 | 108.88 ± 3.81 | 101.69 ± 2.35 | 11.26 ± 0.35 |
Rem2flx/flx + AAV-GFP-CRE | −69.38 ± 0.59 | 101.26 ± 2.68 | 96.75 ± 2.59 | 9.66 ± 0.31 |
10–12 days post infection Rem2flx/flx + AAV GFP |
−64.04 ± 0.56 | 105.87 ± 3.75 | 111.54 ± 3.62 | 11.35 ± 0.39 |
Rem2flx/flx + AAV-GFP-CRE | −64.21 ± 0.44 | 122.07 ± 3.10 | 102.56 ± 2.42 | 12.30 ± 0.37 |
*p≤0.05 compared to WT TR or #p≤0.05 compared to Rem2-/- TR by a two-way ANOVA followed by a Tukey test. All other comparisons are not significant. For Rem2flx/flx mice, data is compared using an independent student’s t-test.