Table 1.
Baseline characteristics for included studies
| References | Method | N | Patient population (all adult ICU patients) | Age | Male | Timeframe Pmcf measurement |
|---|---|---|---|---|---|---|
| Maas et al. [21] | Pmcf hold | 12 | Postoperative cardiac surgery | 64 (10) | 10 (83%) | Not described |
| 10 CABG | ||||||
| 2 AVR | ||||||
| Keller et al. [23] | Pmcf hold | 9 | Postoperative cardiac surgery | Median 61 | 4 (44%) | Not described |
| 3 CABG | IQR 55–75 | |||||
| 6 AVR | ||||||
| Maas et al. [22] | Pmcf hold | 10 | Postoperative cardiac surgery | 64 (11) | 9 (90%) | Within 1 h after ICU admission |
| 2 AVR | ||||||
| 1 MVP + TVP | ||||||
| 7 CABG | ||||||
| Persichini et al. [27] | Pmcf hold | 16 | Septic shock | 67 (16) | 8 (50%) | Not described |
| Maas et al. [25] | Pmcf hold | 16 | Postoperative cardiac surgery | 64 (11) | Not described | Within 1 h after ICU admission |
| 1 MVP | ||||||
| 15 CABG | ||||||
| Guerin et al. [28] | Pmcf hold | 30 | Shock | 65 (12) | 21 (70%) | Not described |
| De Wit et al. [24] | Pmcf hold | 17 | Postsurgical gastrointestinal | 62 (9) | 14 (82%) | Not mentioned |
| 16 esophageal resection | ||||||
| 1 pancreaticoduodenectomy | ||||||
| Helmerhorst et al. [26] | Pmcf hold | 22 | Postoperative cardiac surgery | 63 (59–66) | 17 (85%) | 1 h after ICU admission |
| 22 CABG | ||||||
| Geerts et al. [43] | Pmcf arm | 24 | Postoperative cardiac surgery | 64 (10) | 19 (79%) | Within 2 h after ICU admission |
| 17 CABG | ||||||
| 7 CABG plus valve repair | ||||||
| Aya et al. [41] | Pmcf arm | 20 | Postoperative cardiac surgery | 63 (11) | 17 (85%) | Initial period at ICU (not further defined) |
| 13 CABG | ||||||
| 4 AVR | ||||||
| 4 MVR | ||||||
| Aya et al. [42] | Pmcf arm | 80 | Postoperative cardiac surgery | 70 | 62 (78%) | Initial period at ICU (not further defined) |
| 36 CABG | Range 52–80 | |||||
| 27 AVR + CABG | ||||||
| 12 MVR + CABG | ||||||
| 5 Other | ||||||
| Parkin et al. [49] | Pmcf analogue | 10 | Multi-organ failing patients receiving CVVH for acute renal failure | 65 | 7 (70%) | Not described |
| Range 24–77 | ||||||
| Cecconi et al. [48] | Pmcf analogue | 39 | 22 Cardiac surgery | 68 (12) | 26 (67%) | Not described |
| 8 Shock | ||||||
| 6 Non-cardiac surgery | ||||||
| 3 Other | ||||||
| Gupta et al. [20] | Pmcf analogue | 61 | Postoperative cardiac surgery | 63 (11) | 46 (75%) | Within 6 h after ICU admission |
| 40 CABG | ||||||
| 8 CABG + valve replacement | ||||||
| 8 Valve replacement | ||||||
| 5 Bentall’s procedure | ||||||
| 7 DDD pacing | ||||||
| Aya et al. [51] | Pmcf analogue | 26 | Postoperative fluid challenge | 68 | 16 (62%) | Initial period at ICU (not further defined) |
| 7 Cardiac surgery | Range 53–80 | |||||
| 19 Non-cardiac surgery | ||||||
| Maas et al. [16] | Pmcf hold | 11 | Postoperative cardiac surgery | 64 | 9 (82%) | Within 2 h after ICU admission |
| Pmcf arm | 11 | 9 CABG | Range 50–80 | |||
| Pmcf analogue | 11 | 2 AVR | ||||
| Maas et al. [30] | Pmcf arm | 15 | Postoperative cardiac surgery | 64 (11) | Not described | Within 1 h after ICU admission |
| Pmcf hold | 12 | 9 CABG | ||||
| 5 Valve | ||||||
| 1 CABG + valve |
Age is presented as mean with standard deviation (SD) or median with range or interquartile range (IQR). Number of males per study is presented as counts with percentage
CABG coronary artery bypass, MVR mitral valve replacement, MPV mitral valve prolapse, AVR aortic valve replacement, TVP tricuspid valve prolapse, CVVH continuous veno-venous hemodiafiltration