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. 2018 Jun 20;8:9410. doi: 10.1038/s41598-018-27400-6

Table 1.

Cytotoxicity of generation 3-, generation 4- and generation 5- DAB dendrimers conjugated with PEG of various molecular weights, expressed as IC50 values, on B16F10-Luc cancer cells (n = 15).

Dendrimer generation IC50 (µg/mL) (mean ± S.E.M.)
No PEG PEG-2K PEG-5K PEG-10K
G3 33.84 ± 2.13 >180 >180 >180
G4 16.34 ± 0.51 55.49 ± 1.70 40.96 ± 1.18 >60
G5 6.04 ± 0.21 22.97 ± 0.67 21.65 ± 0.41 55.05 ± 2.38