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. 2018 Jun 14;9:1350. doi: 10.3389/fimmu.2018.01350

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Copyright © 2018 Marin-Palma, Castro, Cardona-Arias, Urcuqui-Inchima and Hernandez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNA expression of inflammasome-related genes in human immunodeficiency virus type 1 (HIV-1)-infected individuals and healthy controls. RNA samples obtained from HIV-1-infected individuals and controls were quantified by real-time PCR: (A) NLRP3, (B) NLRP1, (C) NLRC4, (D) AIM2, (E) ASC, (F) caspase-1, (G) IL-18, and (H) IL-1β. β-Actin was used as the constitutive gene to normalize the RNA content. The statistical comparison was made using the Mann–Whitney U test with a 95% confidence level. Significant differences are represented in the upper part of this figure (*p < 0.05; **p < 0, 01; and ***p < 0.0001).