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. 2018 Jun 14;9:1297. doi: 10.3389/fimmu.2018.01297

Figure 6.

Figure 6

Sting and cGas restrict ectromelia virus (ECTV) replication in RAW264.7 cells. Sting−/−, cGas−/−, and wild-type (WT) cells were infected with ECTV at an MOI of 0.1 (A) or 5 (B). After a 2-h incubation, the supernatants were replaced with fresh medium supplemented with 1% fetal bovine serum, and then the supernatants were collected at the indicated time points for viral titer measurements by using the plaque assay. All the data represent mean ± SD of biological triplicates from at least three independent experiments. The data were analyzed using a one-way analysis of variance followed by the Duncan’s multiple range test (**P ≤ 0.01 and ***P ≤ 0.001).