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. 2018 Jun 14;9:635. doi: 10.3389/fphar.2018.00635

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Copyright © 2018 Liou, Cheng, Yeh, Wu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of casticin (CAS) on asthmatic lung tissue. Histological sections of lung tissues from normal (N) and OVA-stimulated (OVA) mice with or without prednisolone (P) and CAS treatment. (A) CAS reduced eosinophil infiltration (H&E stain; 200× magnification). (B) Periodic acid-Schiff (PAS)-stained lung sections show goblet cell hyperplasia (200× magnification). (C) Results are expressed as the number of PAS-positive cells per 100 μm of basement membrane. The data are presented as means ± SEM of three independent experiments (n = 6). ^∗p < 0.05, ^∗∗p < 0.01 compared to the OVA control group.