Figure 2.

(A) Percentage of dipeptidyl peptidase IV (DPP-IV) inhibition observed with the peptides of the minimum analog peptide set evaluated at 500 µM. Values are mean ± SD (n = 3). (B) Coefficients of the model (β₀–β₉; Eq. 2) linking the % DPP-IV inhibition of the peptides at 500 µM to their hydrophobicity (v₃). (C) Predicted vs. experimental % DPP-IV inhibition of peptides from set #1 (diamonds) and set #2 (squares) evaluated at 500 µM. The line represents the multilinear regression model determined with data from peptide set #1 (Eq. 2).