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. 2018 Jun 14;9:1231. doi: 10.3389/fimmu.2018.01231

Figure 2.

Figure 2

DC-SIGN and its cargo quickly dissociate upon internalization. (A) Time-course of the median internalization score of monocyte-derived DCs triggered with AF405-labeled AZN-D1 and stained intracellular against DC-SIGN (n > 5,000). (B) Scatter plot of the internalization scores of both ligand and receptor 7.5 min after triggering with AF405-labeled AZN-D1 (n > 5,000). (C) Time-course of the median co-localization of AF405-labeled AZN-D1 and DC-SIGN (n > 5,000). (D) Time-course of the fluorescence signal intensity of both AF405-labeled AZN-D1 and DC-SIGN (n > 5,000).