Table 1.
% of CGRP+ (Arch/CGRP) | |
---|---|
Cre− | Cre+ |
0.000 ± 0.000 (0/372) | 94.520 ± 0.591 * (508/539) |
aArch+ fibers and CGRP antibody staining in DRGs overlap extensively. Counts were from sections of lumbar 1–6 DRG from CGRP-Arch Cre− and Cre+ animals (5–11 representative sections per animal, n = 3 per genotype). The percentage of Arch-GFP+, CGRP+ neurons was calculated for Cre− and Cre+ animals. Cre− animals did not express Arch-GFP, whereas Arch+ fibers extensively overlapped with CGRP antibody staining in Cre+ animals. The exact number of neurons counted for each animal is shown in parentheses below the percentage. Percentages are mean ± SEM.
*p < 0.0001 (unpaired t test).